Profiles
Susan Hsiao, Ph.D.
Fellow in Clerkship, Cellular and Molecular Biology
NIH CMB Training Grant
BS, Cornell
Email:
Faculty Mentor: Susan Smith, Ph.D.
Thesis
Analysis of Tankyrase 1 and Tankyrase 2 in Human Cells and Mouse Models
Research Interests
Telomeres; Tankyrase 1 and 2; Poly (ADP-ribose) polymerases; Mitosis and cell cycle regulation; Cohesin
Selected Publications
Hsiao SJ*, Vaynrub M*, Furer V, Samuels J. Polyarticular Gout Attacks Following Cerebrovascular Accidents: Is Hemiparesis Protective? J Clin Rheumatol. Forthcoming 2009.
Hsiao SJ, Smith S. Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ. J Cell Biol. 2009 Feb 23;184(4):515-26. Epub 2009 Feb 16. Cited in Pubmed; PMID 19221198. doi: 10.1083/jcb.200810132.
Chiang YJ, Hsiao SJ, Yver D, Cushman SW, Tessarollo L, Smith S, Hodes RJ. Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development. PLoS ONE. 2008 Jul 9;3(7):e2639. Cited in Pubmed; PMID 18612384. doi: 10.1371/journal.pone.0002639. PMCID: PMC2441437.
Hsiao SJ, Smith S. Tankyrase function at telomeres, spindle poles, and beyond (Review). Biochimie. 2008 Jan;90(1):83-92. Epub 2007 Jul 24. Cited in Pubmed; PMID 17825467. doi: 10.1016/j.biochi.2007.07.012.
Hsiao SJ, Poitras MF, Cook BD, Liu Y, Smith S. Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping. Mol Cell Biol. 2006 Mar;26(6):2044-54. Cited in Pubmed; PMID 16507985. doi: 10.1128/MCB.26.6.2044-2054.2006. PMCID: PMC1430302.
Kim MY, Hsiao SJ, Kraus WL. A role for coactivators and histone acetylation in estrogen receptor alpha-mediated transcription initiation. EMBO J. 2001 Nov 1;20(21):6084-94. Cited in Pubmed; PMID 11689448. doi: 10.1093/emboj/20.21.6084.