Profiles
Santosha Vardhana, Ph.D.
Fellow in Clerkship, Molecular Oncology and Immunology
University of Pennsylvania
Email:
Faculty Mentor: Michael Dustin, Ph.D.
Thesis
Ubiquitin binding by TSG101 prevents chronic T cell receptor signaling in the immunological synapse
Selected Publications
Tseng SY, Waite JC, Liu M, Vardhana S, Dustin ML. T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase Ctheta. J Immunol. 2008 Oct 1;181(7):4852-63. Cited in Pubmed; PMID 18802089. PMCID: PMC2556893.
Vardhana S, Dustin M. Supported Planar Bilayers for the Formation of Study of Immunological Synapses and Kinapse (video protocol). J Vis Exp. 2008 Sep 15;19:pii: 947. Cited in Pubmed; PMID 19066534. doi: 10.3791/947.
Kirchhof MG, Chau LA, Lemke CD, Vardhana S, Darlington PJ, Márquez ME, Taylor R, Rizkalla K, Blanca I, Dustin ML, Madrenas J. Modulation of T cell activation by stomatin-like protein 2. J Immunol. 2008 Aug 1;181(3):1927-36. Cited in Pubmed; PMID 18641330.