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Maureen Nemetski

Graduate Student, Molecular Pharmacology and Signal Transduction
NRSA Ruth L. Kirschstein Individual Predoctoral MD/PhD Fellowship
BA Molecular Biology, Princeton University
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Faculty Mentor: Timothy Cardozo, M.D., Ph.D.

After failing to convince her AP Chemistry teacher to blow things up every day, Maureen chose to enter the lab herself. Despite her daughter’s wish to move to Antarctica and study penguins, she opted to focus on human pathogens. She uses computational tools to predict malarial protein structures and design drugs against them, all while avoiding pipettes as much as possible. When not at the computer in lab, Maureen enjoys sitting at the computer at home visiting the Sesame Street website with her kids.

Thesis

Elucidation of the Structural Basis of the Biomolecular Interactions among Protein Components of the Plasmodium falciparum Motor Complex and the Rational Design of an Inhibitor of this Complex

Research Interests

computational biology; rational drug design; protein structure prediction; infectious diseases; microbiology; cardiology, atherosclerosis, lipid and glucose metabolism

Selected Publications

Cardozo T, Nemetski SM, Abagyan R, Mueckler M, Wang D. Homology modeling reveals the rotational trajectory of the Glut1 transport mechanism. Forthcoming 2009.
Nemetski SM, Gardner LB. Hypoxic regulation of Id-1 and activation of the unfolded protein response are aberrant in neuroblastoma. J Biol Chem. 2007 Jan 5;282(1):240-8. Epub 2006 Nov 13. Cited in Pubmed; PMID 17102133. doi: 10.1074/jbc.M607275200.
Brodkin ES, Hagemann A, Nemetski SM, Silver LM. Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice. Brain Res. 2004 Mar 24;1002(1-2):151-7. Cited in Pubmed; PMID 14988045. doi: 10.1016/j.brainres.2003.12.013.
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