Profiles
Jonathan Feig, Ph.D.
Fellow in Clerkship, Cellular and Molecular Biology
NIH Fellowship
BA Chemistry, Brooklyn College
Email:
Faculty Mentor: Edward Fisher, M.D., Ph.D., M.P.H.
My interests in science have led me to pursue a MD/PhD degree. When I am not in the lab, you can find me helping others.
Thesis
The regression of atherosclerosis: Molecular insights from novel mouse models
Research Interests
Role of transcription factors in the pathogenesis of atherosclerosis
Selected Publications
Torra IP, Ismaili N, Feig JE, Xu CF, Cavasotto C, Pancratov R, Rogatsky I, Neubert TA, Fisher EA, Garabedian MJ. Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. Mol Cell Biol. 2008 Apr;28(8):2626-36. Epub 2008 Feb 4. Cited in Pubmed; PMID 18250151. PMCID: PMC2293109.
Feig JE, Shamir R, Fisher EA. Atheroprotective effects of HDL: beyond reverse cholesterol transport. Curr Drug Targets. 2008 Mar;9(3):196-203. Cited in Pubmed; PMID 18336237.
Williams KJ, Feig JE, Fisher EA. Rapid regression of atherosclerosis: insights from the clinical and experimental literature. Nat Clin Pract Cardiovasc Med. 2008 Feb;5(2):91-102. Cited in Pubmed; PMID 18223541.
Shamir R, Feig JE, Fisher EA. Therapeutic approach to childhood hypercholesterolemia. Pediatr Endocrinol Rev. 2007 Dec;5(2):649-55. Cited in Pubmed; PMID 18084159.
Williams KJ, Feig JE, Fisher EA. Cellular and molecular mechanisms for rapid regression of atherosclerosis: from bench top to potentially achievable clinical goal. Curr Opin Lipidol. 2007 Aug;18(4):443-50. Cited in Pubmed; PMID 17620862.
Hyafil F, Cornily JC, Feig JE, Gordon R, Vucic E, Amirbekian V, Fisher EA, Fuster V, Feldman LJ, Fayad ZA. Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography. Nat Med. 2007 May;13(5):636-41. Epub 2007 Apr 8. Cited in Pubmed; PMID 17417649.
Weinreb DB, Aguinaldo JG, Feig JE, Fisher EA, Fayad ZA. Non-invasive MRI of mouse models of atherosclerosis. NMR Biomed. 2007 May;20(3):256-64. Cited in Pubmed; PMID 17451174.
Trogan E, Feig JE, Dogan S, Rothblat GH, Angeli V, Tacke F, Randolph GJ, Fisher EA. Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3781-6. Epub 2006 Mar 1. Cited in Pubmed; PMID 16537455. doi: 10.1073/pnas.0511043103. PMCID: PMC1450154.
Yoshida H, Feig JE, Morrissey A, Ghiu IA, Artman M, Coetzee WA. K ATP channels of primary human coronary artery endothelial cells consist of a heteromultimeric complex of Kir6.1, Kir6.2, and SUR2B subunits. J Mol Cell Cardiol. 2004;37(4):857-69. Cited in Pubmed; PMID 15380676.
