Profiles

Francisco Ramírez-Valle, M.D., Ph.D.

Current Position:
PGY-1 Resident in Preliminary Medicine, Brigham & Women’s Hospital, Boston; followed by PGY-2 Dermatology (Research Track), University of California, San Francisco.
Graduate: 2009, Microbiology
William Randolph Hearst Foundation Fellow
AΩA Medical Honor Society
BS, Microbiology, University of Rochester
Faculty Mentor: Robert Schneider, Ph.D.

I will be a PGY-1 Resident in Preliminary Medicine at Brigham & Women's Hospital, Boston. Next year I will continue my PGY-2 in Dermatology (Research Track) at the University of California, San Francisco. My clinical interests involve cutaneous manifestations of connective tissue diseases. My scientific interests include immune deregulation in connective tissue disease and host-pathogen interactions.

Thesis

Signaling and Translational Control of Nutrient Sensing and Cell Cycle by the mTOR-raptor-eIF4GI Junction

Selected Publications

Ramírez-Valle F, Braunstein S, Narasimhan M, Schneider RJ. Mitosis-specific Modification of raptor Increases mTORC1 Activity During G2/M. Curr Bio. Forthcoming 2009.

Ramírez-Valle F, Braunstein S, Zavadil J, Formenti SC, Schneider RJ. eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J Cell Biol. 2008 Apr 21;181(2):293-307. Cited in Pubmed; PMID 18426977. doi: 10.1083/jcb.200710215. PMCID: PMC2315676.

Wakem P, Ramirez F, Zlotnick D, Gaspari AA. Heterogeneity of CD80 gene transcription by human keratinocytes to allergens and irritants: relevance to allergic contact dermatitis in vivo. J Appl Toxicol. 2004 Nov;24(6):485-92. Cited in Pubmed; PMID 15558838. doi: 10.1002/jat.1003.

Wakem P, Burns RP Jr, Ramirez F, Zlotnick D, Ferbel B, Haidaris CG, Gaspari AA. Allergens and irritants transcriptionally upregulate CD80 gene expression in human keratinocytes. J Invest Dermatol. 2000 Jun;114(6):1085-92. Cited in Pubmed; PMID 10844549. doi: 10.1046/j.1523-1747.2000.00997.x.